ACTION BY TOXIC AGENTS.
نویسندگان
چکیده
منابع مشابه
Modes of action of toxic agents.
The principal modes of action of toxic agents are discussed in relation to the type of chemical bond formed between the poison and the target constituent of tissues. Alteration of enzyme activity, interference with the binding of poisonous chemicals to proteins, intercalation with nucleic acids, disturbances in electrolyte balance and the disorganization of cellular water and membrane lipids ar...
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The effect of various toxic agents on granulocytes or their precursors is reviewed with emphasis on hypoplastic anemia, granylocytopenia (toxic, idiosyncratic and immune), leukemia and morphologic cytoplasmic and nuclear changes.
متن کاملBiochemical Studies of Toxic Agents
The determination ofthe so-called 'ethereal sulphate content' of urine is a simple analytical procedure, and there are many reports in the literature which show that the administration of phenols to experimental animals is followed by an increased excretion ofethereal sulphates in the urine. On the other hand, because of the difficulties which have usually been encountered, relatively few ether...
متن کاملBiochemical Studies of Toxic Agents
1. The metabolism of cisand trans-acenaphthene-1,2-diol has been studied after the administration of these compounds to rats by subcutaneous injection and by stomach tube. 2. 1,8-Naphthalic acid has been isolated as its anhydride from the urine of the dosed animals. 3. A spectrophotometric method for the determination of free and conjugated 1,8-naphthalic acid in urine has been developed and ha...
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Toxic solutions applied at one end of a Nitella cell 6 cm. long may produce little or no visible change in the structure of the protoplasm at the place of application but if the opposite end is covered with water its protoplasm soon disintegrates. If the middle of the cell is covered with mineral oil this region remains normal in appearance for half an hour or more. The result is due to the mov...
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ژورنال
عنوان ژورنال: Journal of the American Medical Association
سال: 1899
ISSN: 0002-9955
DOI: 10.1001/jama.1899.92450530003002